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While most chemicals in cosmetics present slight or zero danger, some have been associated with severe health issues, such as neurological harm and cancer. Cosmetic chemicals gain entry to a person's body through internal use, the skin, and inhalation, and lead to the same dangers as food chemicals, per this site.

Chemicals linked to cancer can be found in food and many other commonly used items. But, no classification of consumer items is subject to less government inspection than cosmetics, including Charm Gel Polish. Although many of the contaminants and chemicals in cosmetics and personal care products likely pose little risk, being exposed to some is linked to worrying health concerns, including cancer.