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While the majority of chemicals in beauty products and cosmetics pose minimal or zero threat, dozens are associated to severe health issues, including cancer, and neurological harm. Chemicals in cosmetics enter a person's body through the skin and inhalation, and lead to the same dangers as food chemicals, per this site.

Chemicals associated with cancer are found in food, water, and several other commonly used products. Yet, no area of consumer products is accountable to less government management than cosmetics, including Groovy Gel Polish. Though most of the chemicals and contaminants in cosmetics very likely present little risk, being exposed to some has been associated with major health problems, including cancer.