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While the majority of chemicals in cosmetics present slight or absolutely no risk, several dozen are linked to serious medical conditions, such as cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics gain entry to a person's body through internal use, the skin, and inhalation, and lead to the same problems as food chemicals, per this site.

Contaminants and chemicals associated with cancer can be found in water, food, and various other ordinary goods. However, no category of consumer goods is susceptible to less government oversight than cosmetics and other personal products, including On Sale Soak Off Gel Polish. While most of the chemicals and contaminants in cosmetics most likely present minimal risk, subjection to some has been associated with critical health concerns, such as cancer.