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Although many chemicals in cosmetics present little or absolutely no risk, several dozen have been associated to severe medical issues, including developmental delays and cancer. Cosmetic chemicals gain entry to a person's body through the skin and inhalation, and cause the same dangers as food chemicals, per this site.

Chemicals and contaminants linked to cancer can be found in food, water, and various other commonly used products. However, no classification of consumer products is susceptible to less government direction than cosmetics and other personal care products, including Intoxication Soak Off Gel Polish. Though most of the chemicals and contaminants in cosmetics in all likelihood present little risk, exposure to some has been linked to significant health problems, such as cancer.