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While many chemicals in cosmetics present minimal or no risk, several dozen have been linked with considerable medical problems, such as cancer, and neurological harm. Cosmetic chemicals gain entry to the body through the skin and inhalation, and pose similar problems as food chemicals, per this site.

Chemicals and contaminants associated with cancer can be found in food, water, and several other commonly used items. Still, no group of consumer items is accountable to less government management than cosmetics, including Glitter Fool's Gold Soak Off Gel Polish. Although most of the contaminants and chemicals in cosmetics almost certainly present very little risk, exposure to a few has been associated with major health conditions, such as cancer.