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While many chemicals in cosmetic products present hardly any or absolutely no danger, several dozen are associated to serious medical conditions, including developmental delays and cancer. Chemicals in cosmetics get into a person's body through ingestion, inhalation, and internal use, and lead to similar dangers as food chemicals, per this site.

Chemicals associated with cancer are found in food, water, and many other ordinary products. Yet, no classification of consumer products is accountable to less government inspection than cosmetics and other personal products, including Gel Polish Pearl. While many of the chemicals and contaminants in cosmetics likely present minimal risk, exposure to a few has been associated with worrying health problems, such as cancer.