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Though most chemicals in cosmetics present little or zero danger, dozens are linked to considerable medical conditions, such as cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals gain entry to the body through internal use, the skin, and inhalation, and lead to similar risks as food chemicals, per this site.

Contaminants and chemicals associated with cancer can be found in water, food, and various other everyday products. Still, no type of consumer products is subject to less government inspection than cosmetics, including Gel Polish Pearl. While many of the chemicals and contaminants in cosmetics and personal care products very likely pose minimal risk, being exposed to a few has been associated with critical health disorders, such as cancer.