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Although the majority of chemicals in beauty products present limited or zero threat, some are linked to severe medical issues, such as developmental delays and cancer. Chemicals in cosmetics gain entry to a person's body through the skin and inhalation, and lead to the same problems as food chemicals, per this site.

Chemicals and contaminants associated with cancer can be found in food and a lot of other ordinary goods. But, no type of consumer goods is subject to less government management than cosmetics and other personal care products, including Custom Kicks. While most of the contaminants and chemicals in cosmetics probably pose minimal risk, exposure to some has been associated with worrying health conditions, including cancer.