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While most chemicals in cosmetic products present slight or no danger, dozens are associated to substantial medical conditions, such as cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals invade the body through the skin and inhalation, and lead to the same risks as food chemicals, per this site.

Chemicals and contaminants linked to cancer can be found in food, water, and several other commonly used goods. Still, no sector of consumer goods is susceptible to less government inspection than cosmetics, including Custom Kicks. While most of the chemicals in cosmetics probably pose very little risk, exposure to a few is linked to significant health concerns, including cancer.