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Although many chemicals in beauty products present limited or no threat, several are linked to substantial medical conditions, such as developmental delays and cancer. Cosmetic chemicals enter the body through the skin and inhalation, and pose the same dangers as food chemicals, per this site.

Chemicals associated with cancer can be found in food and many other ordinary items. Still, no group of consumer items is accountable to less government management than cosmetics and other personal care products, including Cowgirl Up. Though most of the chemicals in cosmetics likely present very little risk, being exposed to a few has been associated with significant health concerns, such as cancer.