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While many chemicals in beauty products and cosmetics present minimal or zero threat, some have been associated to significant medical problems, such as developmental delays and cancer. Chemicals in cosmetics can enter a person's body through inhalation, the skin, and ingestion, and pose similar problems as food chemicals, per this site.

Contaminants and chemicals linked to cancer are found in water, food, and many other ordinary products. But, no sector of consumer products is accountable to less government direction than cosmetics, including Tangerine Dream Gel. Although most of the contaminants and chemicals in cosmetics and personal care products most likely present minimal risk, subjection to a few has been linked to major health issues, such as cancer.