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Although most chemicals in beauty products present limited or zero threat, some have been associated to severe medical issues, including cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals can enter a person's body through the skin and inhalation, and lead to similar risks as food chemicals, per this site.

Contaminants and chemicals associated with cancer are found in food, water, and various other everyday goods. Still, no sector of consumer goods is susceptible to less government direction than cosmetics and other personal products, including Essence of Pearl. While many of the chemicals in cosmetics most likely present minimal risk, exposure to a few is associated with serious health conditions, such as cancer.