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Though the majority of chemicals in cosmetics pose hardly any or absolutely no risk, several dozen have been associated with serious medical problems, including cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics enter a person's body through the skin, inhalation, ingestion and internal use, and pose similar dangers as food chemicals, per this site.

Contaminants and chemicals associated with cancer are found in food, water, and many other commonly used items. However, no area of consumer items is accountable to less government oversight than cosmetics, including Tip Toe Nail Polish. Though most of the chemicals in cosmetics likely present very little risk, being exposed to some is associated with significant health concerns, including cancer.