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While the majority of chemicals in cosmetics pose very little or no danger, dozens are associated with substantial medical problems, including neurological harm and cancer. Chemicals in cosmetics invade a person's body through internal use, the skin, and inhalation, and lead to the same problems as food chemicals, per this site.

Chemicals associated with cancer can be found in food, water, and several other common products. However, no sector of consumer products is subject to less government management than cosmetics, including Infamous. While most of the contaminants and chemicals in cosmetics almost certainly pose little risk, being exposed to a few has been associated with critical health issues, including cancer.