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Though the majority of chemicals in beauty products and cosmetics pose hardly any or zero threat, several are associated with significant health conditions, including developmental delays and cancer. Chemicals in cosmetics gain entry to a person's body through the skin and inhalation, and lead to similar risks as food chemicals, per this site.

Chemicals linked to cancer are found in water, food, and various other commonly used products. Yet, no classification of consumer products is accountable to less government oversight than cosmetics and other personal care products, including Nicole by OPI. While many of the chemicals and contaminants in cosmetics and personal care products in all likelihood pose very little risk, subjection to a few is linked to worrying health issues, including cancer.