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Though most chemicals in cosmetic products pose limited or no risk, dozens have been associated to severe medical issues, including developmental delays and cancer. Cosmetic chemicals enter the body through ingestion, inhalation, and internal use, and lead to the same risks as food chemicals, per this site.

Chemicals linked to cancer can be found in food, water, and a lot of other everyday products. However, no category of consumer products is accountable to less government inspection than cosmetics and other personal care products, including Nicole by OPI. Though most of the chemicals in cosmetics and personal care products probably pose minimal risk, being exposed to some is linked to serious health conditions, such as cancer.