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While the majority of chemicals in cosmetic products present hardly any or zero risk, several have been linked to serious medical conditions, such as cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals gain entry to a person's body through inhalation, ingestion, and the skin, and pose the same problems as food chemicals, per this site.

Chemicals and contaminants associated with cancer can be found in water, food, and various other ordinary products. Still, no sector of consumer products is accountable to less government inspection than cosmetics, including Nail Enamel- All Fired Up. While most of the chemicals and contaminants in cosmetics in all likelihood present minimal risk, subjection to some has been associated with major health concerns, such as cancer.