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While many chemicals in cosmetics present hardly any or zero risk, several dozen have been associated to severe medical conditions, such as cancer, and neurological harm. Chemicals in cosmetics can enter a person's body through ingestion, inhalation, and internal use, and lead to similar risks as food chemicals, per this site.

Chemicals and contaminants linked to cancer can be found in food, water, and various other common products. However, no category of consumer products is susceptible to less government management than cosmetics and other personal care products, including Sally Hansen 5 Minute French Manicure. While most of the chemicals and contaminants in cosmetics and personal care products in all likelihood present minimal risk, subjection to some is linked to critical health disorders, including cancer.