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While the majority of chemicals in cosmetics pose very little or absolutely no risk, dozens have been associated to serious health problems, including developmental delays and cancer. Cosmetic chemicals enter a person's body through inhalation, ingestion, and the skin, and lead to the same dangers as food chemicals, per this site.

Chemicals and contaminants associated with cancer can be found in water, food, and many other ordinary items. Still, no type of consumer items is accountable to less government direction than cosmetics and other personal care products, including Sally Hansen Mega Shine. Though most of the contaminants and chemicals in cosmetics most likely pose minimal risk, being exposed to a few has been associated with critical health disorders, including cancer.