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While the majority of chemicals in cosmetics present slight or no threat, some have been associated to substantial health issues, including cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics can enter a person's body through the skin and inhalation, and lead to similar risks as food chemicals, per this site.

Chemicals associated with cancer can be found in food, water, and many other common goods. Still, no kind of consumer goods is subject to less government inspection than cosmetics, including Professional Nail Lacquer - Pacific Sunset. Although many of the contaminants and chemicals in cosmetics and personal care products almost certainly present very little risk, being exposed to a few has been associated with substantial health issues, such as cancer.