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Although the majority of chemicals in cosmetics present hardly any or zero threat, dozens have been associated with severe health issues, such as cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals can enter the body through the skin and inhalation, and cause similar problems as food chemicals, per this site.

Chemicals and contaminants associated with cancer are found in food and various other everyday items. Still, no area of consumer items is susceptible to less government direction than cosmetics, including Sinful Nail Lacquer. Although many of the contaminants and chemicals in cosmetics and personal care products most likely pose minimal risk, exposure to some is associated with significant health issues, such as cancer.