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While most chemicals in cosmetics present slight or absolutely no risk, dozens are associated with substantial health problems, including neurological harm and cancer. Chemicals in cosmetics can enter a person's body through internal use, the skin, and inhalation, and lead to similar dangers as food chemicals, per this site.

Contaminants and chemicals linked to cancer can be found in food, water, and various other common items. However, no group of consumer items is susceptible to less government oversight than cosmetics, including Sinful Colors Nail Polish. Though most of the contaminants and chemicals in cosmetics and personal care products in all likelihood pose little risk, subjection to some has been linked to worrying health conditions, including cancer.