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Although many chemicals in cosmetics present limited or no threat, several are linked with serious health issues, such as cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals can enter the body through inhalation, the skin, and ingestion, and lead to the same problems as food chemicals, per this site.

Chemicals associated with cancer are found in food, water, and a lot of other everyday items. However, no group of consumer items is subject to less government management than cosmetics, including Sinful Colors Nail Polish. Though most of the chemicals in cosmetics likely present very little risk, exposure to some has been associated with worrying health issues, including cancer.