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Although many chemicals in cosmetics present minimal or zero threat, several have been associated with severe medical problems, such as cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics enter a person's body through the skin, inhalation, ingestion and internal use, and lead to the same risks as food chemicals, per this site.

Chemicals associated with cancer are found in food, water, and lots of other everyday goods. But, no category of consumer goods is accountable to less government direction than cosmetics and other personal care products, including Open Your Heart. Though most of the contaminants and chemicals in cosmetics almost certainly pose minimal risk, being exposed to a few has been associated with worrying health issues, such as cancer.